I thought I did…but I was wrong. Like most people I thought muscle and joint pain were caused by too many “to-the-max” workouts, poor technique, not getting enough of the right calories - at the right time, partying or not enough sleep. But according to the latest scientific research, muscle and joint pain after lifting (the kind that makes you wonder if you'll ever walk again…let alone squat another rep) is about, of all things, neutrophil leakage (aka leukocyte adhesion cascade) from the capillary matrix surrounding your joints and throughout your muscles.1,2 What a mouthful!
These tiny blood vessels leak neutrophils (joint inflammation occurs when neutrophils flood to the sites of irritation), which crank up the leukocyte adhesion cascade that plays havoc with your muscles after any decent workout.3
The result is inflammation...and pain.4 What does this all mean in plain English? Inflammation from exercise must happen after workouts to stimulate any cell growth at all. 5,6 But, if left untreated, inflammation, and the resulting stiffness and aches, leads to overtraining and injuries. 7 Doctors call these types of problems “musculo-skeletal injuries.” However when it comes to getting stronger and looking good it doesn't matter what they're called. The results are always the same. Muscle soreness, joint pain, inflammation and overtraining mean lower poundages and perhaps worst of all, loss of size.
Because serious muscle and joint pain after lifting is so difficult to address, many bodybuilders are popping pain pills like Motrin, Advil and Aleve. Unfortunately it is
a little known fact that the medicines in these pain killers, called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), eat away the stomach lining, joint cartilage and bone while reducing muscle power and strength.8,9 This makes long-term recovery and continued cell repair and growth impossible.
Not an ordinary protein muscle builder…a muscle and joint pain breakthrough. Today, it's not surprising that among savvy, in-the-know bodybuilders the hottest new “must have” compound to be quietly shaking up the supplement market is something called Rx-98™ . Why? Because it is the first product specifically developed to dramatically reduce serious muscle and joint pain after exercise…and do it without drugs, steroids, creatine, caffeine or other stimulants.
In published scientific studies, conducted since 1990, the one-of-a-kind patented ingredients in Rx-98 have been shown to reduce inflammation in joints and muscles by slowing neutrophil leakage and blocking the leukocyte adhesion cascade and not surprisingly– increase activity of the key muscle growth gene Pax7 (about 17x's above baseline!). The result - less inflammation - faster muscle recovery - better joint mobility - more strength… and minimal pain after exercise.10,11
Here are two more eye-opening studies. First, serious year-round runners may be skinny, but they train as hard as bodybuilders. During a 6 month study in Tacoma , WA researchers measured the recovery enzyme, creatine kinase and showed that using the patented ingredients in Rx-98 twice a day steadily improves recovery.12
Race recovery times improved an average of 57% while body mass increased 1.6 lbs. As expected, blood neutrophil levels after exercise increased 5.7% which confirms blocking of neutrophil leakage.12
Second, in a 6 week study on older, inactive patients suffering from daily joint pain and stiffness, the patented ingredients in Rx-98 relieved symptoms of everyday joint pain faster than glucosamine.13 But forget about the scientific studies –
Talk to the athletes using Rx-98 ™ and they all say the same thing…amazing. In as little as 14 days or so, serious muscle and joint pain, inflammation and stiffness virtually disappear. Because the longer you take Rx-98 the better the results, after 6 weeks reports are your body can feel looser and recover faster. Even 6 months down the road athletes report sleeping better, staying leaner, having more energy and less joint pain after exercise.
So if muscle and joint pain are of the serious variety then you will need to see a doctor. But if you are like the rest of us who are hurting after lifting, and tired of the potential damage that Motrin, Advil and Aleve can do to your joints, muscles and health…there's only one question - What are you waiting for?
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Claim 1 of 1,2 Ref under “Do you know..workouts?” SH
1.) Pizza, Francis et. al., Muscle Inflammatory Cells after Passive Stretches, Isometric Contractions, and Lengthening Contractions, J Appl Physiol 92: 1873-1878, 2002.
Claim 2 of 1,2 Ref under “Do you know..workouts?” SH
2.) McLoughlin, Thomas et. al ., Inflammatory Cells in Rat Skeletal Muscle are Elevated after Electrically Stimulated Contractions, J Appl Physiol 94: 876-882, 2003.
Claim 3 Ref under “Do you know…workouts” SH …decent workout.
3.) Pizza, Francis et. al., Neutrophils Injure Cultured Skeletal Myotubes, Am J Physiol Cell Physiol 281: C334-C341, 2001.
Claim 4 Ref for “The result is inflammation…and pain” SH
4.) Jones, Anthony K. P. et. al., In Vivo Leukocyte Migration in Arthritis, Arthritis and Rheumatism, Vol. 34, No. 3 (March 1991).
Claim 5 of 5,6 Ref for “The result is inflammation” SH …cell growth at all
5.) Spangenburg, Espen E. et. al., Multiple Signaling Pathways Mediate LIF-Induced Skeletal Muscle Satellite Cell Proliferation, Am J Physiol Cell Physiol 283: C204-C211, 2002.
Claim 6 of 5,6 Ref for “The result is inflammation” SH …cell growth at all
6.) McHugh, M.P. et. al., Exercise-Induced Muscle Damage and Potential Mechanisms for the Repeated Bout Effect , Sports Medicine, Volume 27, Number 3, 1 March 1999, pp. 157-170(14).
Claim 7 for “The result is inflammation” SH…overtraining and injuries.
7.) Cheung, K. et. al., Delayed Onset Muscle Soreness: Treatment Strategies and Performance Factors, Sports Med. 2003;33(2):145-64.
Claim 8 of 8,9 Ref for “Healthier than Motrin…Aleve” SH …reducing muscle power and strength.
8.) Newman , N.M. et. al., Acetabular Bone Destruction Related to Non-Steroidal Anti-Inflammatory Drugs, Lancet 1985; Jul 6;2(8445):11-4.
Claim 9 of 8,9 Ref for “Healthier than Motrin…Aleve” SH …reducing muscle power and strength.
9.) Shield, M.J. Anti-Inflammatory Drugs and Their Effects on Cartilage Synthesis and Renal Function, Eur J Rheumatol Inflamm. 1993; 13(1):7-16.
Claim 10 of 10,11 Ref for Last Sentence under “Where's the Proof?” SH
10.) Stelwagen, K. et. al., An Anti-Inflammatory Component Derived from Milk of Hyperimmunised Cows Reduces Tight Junction Permeability In Vitro, Inflamm. Res. 47(1998) 384-388.
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